When I got my new Cannondale T1 bicycle in November 2009, it had a very unusual saddle. I'd not seen another exactly like it before, nor have I seen one since.
It's a Selle An-Atomica Clydesdale. I gave it a favorable "200-mile report" here. I've really not mentioned it much since, but I've very much enjoyed it. It is, without any doubt, the most comfortable saddle I've ever ridden on.
I recently had occasion to appreciate the comfort level.
For you see - my An-Atomica saddle broke! (Doh!) In mid-February, in the middle of a ride, I noticed it seemed to have considerable extra flex. I rode on home, and discovered that both rails were broken, right behind the seatpost clamp.
I contacted the company, and after the exchange of some information, they agreed to repair it. (Officially it had/has a 1-year warranty, and mine was slightly outside of the warranty period. But we all agreed that a $150 saddle really should last longer than a year.) They told me to send it in. Surprisingly, I just received a replacement brand-new saddle; I expected a new frame, but the same leather (which was still in excellent shape).
During the 3 weeks or so my An-Atomica was "offline," I rode on a more conventional saddle. It's one that I've logged thousands of miles on. And my first impression was, "Hey! This is like sitting on a post!" It was not uncomfortable on the sub-25-mile rides I mostly go on... but there's no doubt in my mind that the "butt hammock" provided by the An-Atomica would be way nicer on a 50-miler, or a multi-day bicycle tour.
I'm optimistic the replacement saddle will last much longer. It has to - no matter how comfortable, I can't justify $150/year saddle expense! (The only other saddle I've broken in 25+ years of riding was a $14.98 "Nashbar special.")
More detailed/technical info about the An-Atomica, and "saddle science," can be found on their website.